Description

Methyl 4-Cyano-2-(Trifluoromethyl)Benzoate is a high-value, multi-functional aromatic ester building block designed for advanced chemical synthesis. Its molecular architecture, featuring both a cyano and a trifluoromethyl group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for electron-deficient aromatic cores in electronic materials for displays and organic light-emitting diodes.
• Functional Polymer Monomer: Incorporated into specialty polymers to impart specific solubility, thermal stability, or optical properties.
• Cross-Coupling Reactions: The ester and cyano groups provide handles for further functionalization via hydrolysis, reduction, or palladium-catalyzed coupling reactions.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	Methyl 4-Cyano-2-(Trifluoromethyl)Benzoate
CAS No.	1641588-74-0
Molecular Formula	C10H6F3NO2
Molecular Weight	229.16 g/mol
Synonyms	Methyl 4-Cyano-2-(trifluoromethyl)benzoate; Benzoic acid, 4-cyano-2-(trifluoromethyl)-, methyl ester; 2-(Trifluoromethyl)-4-cyanobenzoic acid methyl ester; Methyl 2-(trifluoromethyl)-4-cyanobenzoate; 4-Cyano-2-(trifluoromethyl)benzoic Acid Methyl Ester; Methyl 4-Cyano-α,α,α-trifluoro-o-toluate
EINECS	Contact for details

Quality Control

Our Methyl 4-Cyano-2-(Trifluoromethyl)Benzoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.