Description

2-Azaspiro[3.4]Octan-6-Ol Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas. The CAS number for this compound is 1638767-65-3.

Application

This specialized intermediate is designed for high-value synthesis in research and commercial pharmaceutical production.

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• API Development: Serves as a building block for the construction of complex Active Pharmaceutical Ingredients (APIs).
• CNS Drug Discovery: Particularly relevant for research into neurological and psychiatric disorders due to its structural motif.
• Process Chemistry & Scale-up: Suitable for process development from laboratory to pilot and commercial scale synthesis.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.

Basic Information

Product Name	2-Azaspiro[3.4]Octan-6-Ol Hydrochloride
CAS No.	1638767-65-3
Molecular Formula	C7H14ClNO
Molecular Weight	163.65 g/mol
Synonyms	6-Hydroxy-2-azaspiro[3.4]octane hydrochloride; 2-Azaspiro[3.4]octan-6-ol, hydrochloride; 2-Azaspiro[3.4]octan-6-ol HCl; Azaspirooctanol hydrochloride; Spirocyclic azetidine hydrochloride derivative
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[3.4]Octan-6-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and related substances. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.