Description

5-Boc-5-Aza-Spiro[3.4]Octane-2-Methamine is a high-value, protected amine building block used in advanced organic synthesis. This compound is critical for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry: Used in scaffold hopping and lead optimization to introduce spirocyclic and constrained amine motifs, improving the pharmacokinetic properties of molecules.
• Peptidomimetics Synthesis: Serves as a constrained amino acid analog for creating novel peptide-like compounds with enhanced metabolic stability.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Utilized to create tool compounds and probes for studying enzyme function and biological pathways.
• Academic Research: Employed in universities and research institutes for methodological development in synthetic organic chemistry.

Basic Information

Product Name	5-Boc-5-Aza-Spiro[3.4]Octane-2-Methamine
CAS No.	1638767-04-0
Molecular Formula	C13H24N2O2
Molecular Weight	240.34 g/mol
Synonyms	5-Aza-spiro[3.4]octane-2-methanamine, 5-(1,1-dimethylethoxy)carbonyl-; tert-Butyl 2-(aminomethyl)-5-azaspiro[3.4]octane-5-carboxylate; 5-Boc-5-azaspiro[3.4]octan-2-ylmethanamine; 2-(Aminomethyl)-5-azaspiro[3.4]octane-5-carboxylic acid tert-butyl ester; 5-[(tert-Butoxycarbonyl)]-5-azaspiro[3.4]octane-2-methanamine; 5-Boc-5-aza-spiro[3.4]octane-2-methylamine; BOC-5-Aza-Spiro[3.4]Octane-2-Methylamine.
EINECS	Contact for details

Quality Control

Our 5-Boc-5-Aza-Spiro[3.4]Octane-2-Methamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.