Description

β-D-Erythro-Pentofuranose, 4-C-[[(Methylsulfonyl)Oxy]Methyl]-3-o-(Phenylmethyl)-, 1,2-Diacetate 5-Methanesulfonate is a sophisticated, multi-functional carbohydrate derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate and building block, offering precise stereochemical control for the development of complex molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical and fine chemical industries for applications in nucleoside chemistry, prodrug development, and the synthesis of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral precursor in the synthesis of novel nucleoside analogs and antiviral/antitumor agents.
• Prodrug Synthesis: Utilized in the design and construction of prodrugs, where its protecting groups and sulfonate ester functionalities are strategically manipulated.
• Glycosylation Chemistry: Acts as a glycosyl donor or a protected sugar intermediate in stereoselective glycosylation reactions.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic pathways to complex carbohydrates and glycoconjugates.
• Process Chemistry Development: Used for scaling up synthetic routes to high-value target molecules, requiring a reliable and high-purity source.
• Chemical Biology Tool: Can be incorporated into probes or substrates for studying enzyme mechanisms related to carbohydrate metabolism.

Basic Information

Product Name	β-D-Erythro-Pentofuranose, 4-C-[[(Methylsulfonyl)Oxy]Methyl]-3-o-(Phenylmethyl)-, 1,2-Diacetate 5-Methanesulfonate
CAS No.	1638766-68-3
Molecular Formula	C19H26O12S2
Molecular Weight	510.53 g/mol
Synonyms	4-C-[(Methylsulfonyloxy)methyl]-3-O-benzyl-1,2-di-O-acetyl-β-D-erythro-pentofuranose 5-methanesulfonate; 3-O-Benzyl-4-C-[(methylsulfonyloxy)methyl]-1,2-di-O-acetyl-β-D-erythro-pentofuranose 5-methanesulfonate; 1,2-Di-O-acetyl-3-O-benzyl-4-C-[(methylsulfonyloxy)methyl]-β-D-erythro-pentofuranose 5-methanesulfonate; Benzyl-protected pentofuranose methanesulfonate ester; Bn-protected ribose derivative mesylate
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and opened in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.