Description

tert-Butyl n-{2-Azaspiro[3.4]Octan-6-Yl}Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic amine structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with enhanced pharmacological properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs) for clinical research and development.
• Proteolysis Targeting Chimera (PROTAC) Development: Used as a component in the linker or ligand design for targeted protein degradation therapeutics.
• Kinase Inhibitor Synthesis: Employed in the construction of complex heterocyclic cores for potential kinase inhibitor candidates.
• Chemical Biology Probes: Acts as a versatile scaffold for creating molecular probes to study biological pathways and protein function.
• Peptidomimetic Chemistry: Utilized to introduce constrained, spirocyclic motifs into peptide-like structures to improve stability and bioavailability.
• Custom Synthesis & Contract Manufacturing: Supplied for custom synthesis projects requiring high-fidelity, structurally complex amine derivatives.

Basic Information

Product Name	tert-Butyl n-{2-Azaspiro[3.4]Octan-6-Yl}Carbamate
CAS No.	1638761-24-6
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	tert-Butyl (6-amino-2-azaspiro[3.4]octan-2-yl)carbamate; 2-Azaspiro[3.4]octan-6-amine, N-Boc-protected; Boc-2-Azaspiro[3.4]octan-6-amine; N-Boc-2-Azaspiro[3.4]octan-6-amine; tert-Butyl carbamate (2-azaspiro[3.4]octan-6-yl); 1638761-24-6; Boc-ASPO-6-amine
EINECS	Contact for details

Quality Control

Our tert-Butyl n-{2-Azaspiro[3.4]Octan-6-Yl}Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.