Description

3-Amino-7-Boc-1-Oxa-7-Azaspiro[3.5]Nonane is a high-value, protected spirocyclic amine building block essential for modern pharmaceutical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, offering a versatile scaffold for constructing novel drug candidates. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries to create new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of spirocyclic drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore novel chemical space and improve the pharmacokinetic properties of new molecular entities.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component in the linker or ligand design for bifunctional molecules that induce targeted protein degradation.
• Agrochemical Synthesis: Employed as an intermediate in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological pathways and target validation in academic and industrial research settings.

Basic Information

Product Name	3-Amino-7-Boc-1-Oxa-7-Azaspiro[3.5]Nonane
CAS No.	1638759-39-3
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	7-(tert-Butoxycarbonyl)-1-oxa-7-azaspiro[3.5]nonan-3-amine; tert-Butyl 3-amino-1-oxa-7-azaspiro[3.5]nonane-7-carboxylate; 3-Amino-7-Boc-1-oxa-7-azaspiro[3.5]nonane; 1-Oxa-7-azaspiro[3.5]nonane-7-carboxylic acid, 3-amino-, 1,1-dimethylethyl ester; Boc-protected 3-amino-1-oxa-7-azaspiro[3.5]nonane; 3-Amino-7-Boc-1-oxa-7-azaspiro[3,5]nonane; 3-Amino-7-Boc-oxa-7-azaspiro[3.5]nonane
EINECS	Contact for details

Quality Control

Our 3-Amino-7-Boc-1-Oxa-7-Azaspiro[3.5]Nonane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.