Description

Azido-PEG4-α-D-Mannose is a specialized bifunctional linker molecule designed for bioconjugation and chemical biology applications. This compound is critical for researchers and developers who require precise, site-specific attachment of biomolecules, such as antibodies or peptides, to other entities like surfaces, nanoparticles, or drug payloads. It is primarily utilized in the pharmaceutical, diagnostic, and advanced materials sectors for creating targeted drug delivery systems, diagnostic probes, and functionalized biomaterials.

Application

• Bioconjugation Reagent: For the site-specific labeling and crosslinking of proteins, antibodies, and peptides via click chemistry (e.g., copper-catalyzed azide-alkyne cycloaddition).
• Drug Delivery System Development: As a key component in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic platforms.
• Diagnostic Probe Synthesis: Used to create fluorescent, radioactive, or other tagged probes for imaging and detection assays.
• Surface Functionalization: For modifying nanoparticles, chips, or beads with mannose moieties to study carbohydrate-protein interactions or create biosensors.
• Glycobiology Research: As a tool compound for studying lectin binding, immune cell targeting, and other mannose-mediated biological processes.
• Polymer and Biomaterial Science: Serving as a monomer or crosslinker for creating smart hydrogels and bioactive polymers.

Basic Information

Product Name	Azido-PEG4-α-D-Mannose
CAS No.	1632372-86-1
Molecular Formula	C18H33N3O11
Molecular Weight	467.47 g/mol
Synonyms	α-D-Mannopyranoside, 2-azidoethyl 2,3,4,6-tetra-O-acetyl-; 2-Azidoethyl 2,3,4,6-Tetra-O-acetyl-α-D-mannopyranoside; Azido-PEG4-α-D-Mannose tetraacetate; N3-PEG4-α-D-Mannose(OAc)4; 1-Azido-3,6,9,12-tetraoxapentadecan-15-yl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside; Azido tetraethylene glycol α-D-mannoside tetraacetate; Azido-PEG4-Man(OAc)4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized by advanced analytical techniques including NMR, HPLC, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to a quality management system to support our commitment to providing reliable, high-purity biochemical tools.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.