Description

7-Oxaspiro[3.5]nonan-2-amine hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic ether-amine structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is essential for medicinal chemistry teams in pharmaceutical R&D and fine chemical synthesis who require reliable, high-quality intermediates to accelerate drug discovery and process development programs.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, especially in neurological and psychiatric disorder research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its constrained spirocyclic scaffold.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route development for potential APIs.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthetic chemistry and new molecular entity design.
• Fine Chemical Synthesis: Utilized in the preparation of complex, high-value specialty chemicals with specific stereochemical requirements.

Basic Information

Product Name	7-Oxaspiro[3.5]nonan-2-amine hydrochloride
CAS No.	1632228-23-9
Molecular Formula	C8H16ClNO
Molecular Weight	177.67 g/mol
Synonyms	2-Amino-7-oxaspiro[3.5]nonane hydrochloride; 7-Oxaspiro[3.5]nonan-2-amine, hydrochloride; 7-Oxaspiro[3.5]nonane-2-amine HCl; 2-Amino-7-oxaspiro[3.5]nonane HCl; 1632228-23-9; Spiro[3.5]nonan-2-amine, 7-oxa-, hydrochloride; 7-Oxaspiro[3.5]nonan-2-aminium chloride
EINECS	Contact for details

Quality Control

Our 7-Oxaspiro[3.5]nonan-2-amine hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identification by IR and NMR, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.