Description

4,7-Diaza-Spiro[2.5]Octane-7-Carboxylic Acid Benzyl Ester, Hcl Salt is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting complex biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs) and sophisticated organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring constrained spirocyclic frameworks.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies for new therapeutic agents.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the development of inhibitors for various protease enzymes.
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and biological pathways.
• Peptidomimetic Synthesis: Integral for constructing peptidomimetics and conformationally restricted peptide analogs.
• Library Synthesis for Drug Discovery: Used in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	4,7-Diaza-Spiro[2.5]Octane-7-Carboxylic Acid Benzyl Ester, Hcl Salt
CAS No.	1630807-17-8
Molecular Formula	C14H19ClN2O2
Molecular Weight	282.77 g/mol
Synonyms	7-(Benzyloxycarbonyl)-4,7-diaza-spiro[2.5]octane hydrochloride; 4,7-Diaza-spiro[2.5]octane-7-carboxylic acid phenylmethyl ester hydrochloride; Benzyl 4,7-diaza-spiro[2.5]octane-7-carboxylate hydrochloride; 7-Cbz-4,7-diaza-spiro[2.5]octane HCl; 4,7-Diaza-spiro[2.5]octane-7-carboxylate benzyl ester hydrochloride; 1,4-Diaza-spiro[2.5]octane-4-carboxylic acid benzyl ester hydrochloride (tautomeric form); 7-Carbobenzoxy-4,7-diaza-spiro[2.5]octane hydrochloride
EINECS	Contact for details

Quality Control

Our 4,7-Diaza-Spiro[2.5]Octane-7-Carboxylic Acid Benzyl Ester, Hcl Salt is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.