Description

4-Bromo-5-Methoxypyridin-2(1H)-One is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and lactam functionalities, enabling precise molecular construction in complex chemical pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its pyridone core structure.
• Material Science: Serves as a building block for functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a scaffold for constructing more complex heterocyclic systems.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and exploratory research in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	4-Bromo-5-Methoxypyridin-2(1H)-One
CAS No.	1630197-34-0
Molecular Formula	C6H6BrNO2
Molecular Weight	204.02 g/mol
Synonyms	4-Bromo-5-methoxy-2(1H)-pyridinone; 4-Bromo-5-methoxypyridin-2-ol; 2-Hydroxy-4-bromo-5-methoxypyridine; 4-Bromo-5-methoxy-1H-pyridin-2-one; 5-Methoxy-4-bromopyridin-2(1H)-one; 4-Bromo-5-methoxypyridin-2-one; 1630197-34-0
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Methoxypyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.