Description

Methyl 2-(1H-Pyrrolo[2,3-B]Pyridin-5-Yloxy)-4-Bromobenzoate is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, particularly in the creation of novel kinase inhibitors and other targeted therapeutics. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers serving the global life sciences sector.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex target molecules.
• Biochemical Tool Compound: Can be utilized in the development of probes for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-scale production.

Basic Information

Product Name	Methyl 2-(1H-Pyrrolo[2,3-B]Pyridin-5-Yloxy)-4-Bromobenzoate
CAS No.	1630101-71-1
Molecular Formula	C15H11BrN2O3
Molecular Weight	347.17 g/mol
Synonyms	Methyl 4-Bromo-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)benzoate; 4-Bromo-2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)benzoic Acid Methyl Ester; 5-((2-(Methoxycarbonyl)-5-bromophenoxy)-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 5-[[2-(methoxycarbonyl)-5-bromophenyl]oxy]-; 1630101-71-1; 7-Azaindole-5-yloxy benzoate derivative
EINECS	Contact for details

Quality Control

Our Methyl 2-(1H-Pyrrolo[2,3-B]Pyridin-5-Yloxy)-4-Bromobenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical methods is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.