Description

3-Thiophenecarboxylic Acid, 5-Bromo-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)-, Ethyl Ester is a high-purity, multi-functional heterocyclic building block designed for advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates a brominated thiophene moiety linked to a phthalimide-protected amine via an ester linkage, enabling precise chemical modifications. It serves as a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, facilitating the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in creating advanced active ingredients for crop protection products, leveraging its halogenated heterocyclic structure.
• Organic Electronic Materials: Serves as a precursor in the development of conjugated polymers and small molecules for organic semiconductors, OLEDs, and sensors.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes, activity-based probes (ABPs), and PROTACs for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A versatile starting material for custom chemical synthesis services, supporting R&D and scale-up projects.
• Academic & Industrial R&D: Fundamental reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle functionalization.

Basic Information

Product Name	3-Thiophenecarboxylic Acid, 5-Bromo-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)-, Ethyl Ester
CAS No.	1629013-79-1
Molecular Formula	C15H10BrNO4S
Molecular Weight	380.21 g/mol
Synonyms	Ethyl 5-Bromo-2-(1,3-dioxoisoindolin-2-yl)thiophene-3-carboxylate; 2-(5-Bromo-3-(ethoxycarbonyl)thiophen-2-yl)isoindoline-1,3-dione; 5-Bromo-2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)thiophene-3-carboxylic Acid Ethyl Ester; 5-Bromo-2-phthalimidothiophene-3-carboxylic Acid Ethyl Ester; N-(5-Bromo-3-(ethoxycarbonyl)thiophen-2-yl)phthalimide; CAS 1629013-79-1
EINECS	Contact for details

Quality Control

Our production of 3-Thiophenecarboxylic Acid, 5-Bromo-2-(1,3-Dihydro-1,3-Dioxo-2H-Isoindol-2-Yl)-, Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification, to ensure consistency and reliability for your critical applications. Certificates of Analysis (COA) detailing all specifications are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.