Description

1-(4-Bromo-2-Methyl-Phenyl)-2,2,2-Trifluoro-Ethanol is a high-purity fluorinated aromatic alcohol building block. This compound is valued for its unique trifluoroethanol moiety attached to a substituted bromo-methylphenyl ring, which imparts specific electronic and steric properties. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring trifluoroethyl groups for metabolic stability or bioavailability enhancement.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the bromine atom offers a versatile site for further functionalization.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the development of advanced polymers and catalysts.
• Liquid Crystal & OLED Materials: Investigated as a building block for fluorine-containing compounds used in electronic display technologies.
• Cross-Coupling Reactions: The aryl bromide functionality makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, or Buchwald-Hartwig aminations.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on the introduction and effects of fluorinated groups in organic molecules.

Basic Information

Product Name	1-(4-Bromo-2-Methyl-Phenyl)-2,2,2-Trifluoro-Ethanol
CAS No.	1628953-52-5
Molecular Formula	C9H8BrF3O
Molecular Weight	269.06 g/mol
Synonyms	α-(4-Bromo-2-methylphenyl)-2,2,2-trifluoroethanol; 2,2,2-Trifluoro-1-(4-bromo-2-methylphenyl)ethanol; 1-(4-Bromo-2-methylphenyl)-2,2,2-trifluoroethan-1-ol; 4'-Bromo-2'-methyl-α-(trifluoromethyl)benzenemethanol; (4-Bromo-2-methylphenyl)(trifluoromethyl)methanol
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-2-Methyl-Phenyl)-2,2,2-Trifluoro-Ethanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, GC, NMR, and other relevant techniques to confirm compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.