Description

tert-Butyl (2-(2-Hydroxyethoxy)ethyl)(methyl)carbamate is a specialized carbamate derivative featuring a protected amine and a hydrophilic ethoxyethanol chain. This compound is valued as a key synthetic intermediate, particularly in the development of active pharmaceutical ingredients (APIs) and advanced organic materials. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and fine chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of drug candidates, especially those requiring protected amine functionalities and PEG-like linkers for solubility enhancement.
• Proteolysis-Targeting Chimera (PROTAC) Development: Used in the construction of linker components for bifunctional molecules designed for targeted protein degradation.
• Bioconjugation & Linker Chemistry: Serves as a versatile spacer or linker molecule for attaching payloads (e.g., drugs, dyes, probes) to antibodies, proteins, or other biomolecules.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties like hydrophilicity and biodegradability.
• Agrochemical Synthesis: Employed in the research and production of advanced pesticides and herbicides where specific carbamate structures are required.
• Peptide Mimetics & Modifications: Used to introduce non-peptidic, stable linkages and solubility-enhancing groups into peptide-based compounds.

Basic Information

Product Name	tert-Butyl (2-(2-Hydroxyethoxy)ethyl)(methyl)carbamate
CAS No.	1628679-52-6
Molecular Formula	C10H21NO4
Molecular Weight	219.28 g/mol
Synonyms	tert-Butyl N-(2-(2-hydroxyethoxy)ethyl)-N-methylcarbamate; 2-[2-[[(tert-Butoxy)carbonyl](methyl)amino]ethoxy]ethanol; Carbamic acid, N-[2-(2-hydroxyethoxy)ethyl]-N-methyl-, 1,1-dimethylethyl ester; BOC-N-Me-EG2-OH; (2-(2-Hydroxyethoxy)ethyl)(methyl)carbamic acid tert-butyl ester; N-Boc-N-methyl-2,2'-oxybis(ethan-1-amine); tert-Butyl methyl(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)carbamate (common mis-assignment for similar structure)
EINECS	Contact for details

Quality Control

Our tert-Butyl (2-(2-Hydroxyethoxy)ethyl)(methyl)carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and cGMP intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.