Description

cis-tert-Butyl 3-Amino-2-Methylpiperidine-1-Carboxylate is a high-purity, protected piperidine derivative serving as a critical chiral building block in advanced organic synthesis. This compound is essential for pharmaceutical research and development, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where specific stereochemistry is required for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioactive Molecule Synthesis: The protected amino-piperidine scaffold is valuable for constructing peptide analogs and other bioactive compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological targets and pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental building block supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	cis-tert-Butyl 3-Amino-2-Methylpiperidine-1-Carboxylate
CAS No.	1628258-95-6
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	1-Boc-3-amino-2-methylpiperidine (cis); (3S,6R)-tert-Butyl 3-amino-2-methylpiperidine-1-carboxylate; (3R,6S)-tert-Butyl 3-amino-2-methylpiperidine-1-carboxylate; cis-1-N-Boc-3-amino-2-methylpiperidine; tert-Butyl cis-3-amino-2-methylpiperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-amino-2-methylpiperidine (cis); 2-Methyl-3-aminopiperidine-1-carboxylic acid tert-butyl ester (cis); Boc-3-A-2-Me-piperidine (cis)
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl 3-Amino-2-Methylpiperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric purity and standard identification methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.