Description

Methyl 5-Bromo-2-Chloro-3-Hydroxybenzoate is a high-purity, multi-functional halogenated benzoate ester serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile molecular scaffold with three distinct reactive sites—bromo, chloro, and hydroxy groups—enabling precise, sequential functionalization for complex molecule construction. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its halogenated aromatic structure for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized monomers for specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	Methyl 5-Bromo-2-Chloro-3-Hydroxybenzoate
CAS No.	1627564-31-1
Molecular Formula	C8H6BrClO3
Molecular Weight	265.49 g/mol
Synonyms	5-Bromo-2-chloro-3-hydroxybenzoic acid methyl ester; Methyl 5-bromo-2-chloro-3-hydroxybenzoate; Benzoic acid, 5-bromo-2-chloro-3-hydroxy-, methyl ester; 3-Hydroxy-5-bromo-2-chlorobenzoic acid methyl ester; Methyl 3-hydroxy-5-bromo-2-chlorobenzoate
EINECS	Contact for details

Quality Control

Every batch of Methyl 5-Bromo-2-Chloro-3-Hydroxybenzoate is produced and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency, which is critical for reproducible research and process scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.