Description

(S)-6,6'-Dibromo-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol,99%E.E. is a high-purity, enantiomerically enriched chiral building block of significant synthetic utility. Its value lies in its rigid, spirocyclic structure and brominated phenolic groups, which serve as key intermediates in the synthesis of complex, optically active molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors, particularly for developing novel ligands, catalysts, and active pharmaceutical ingredients (APIs) requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the asymmetric synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Catalyst & Ligand Synthesis: Used to construct sophisticated, enantiopure ligands for transition-metal catalysis in fine chemical manufacturing.
• Advanced Material Research: Serves as a monomer or building block for developing chiral polymers and functional organic materials with specific optical properties.
• Asymmetric Synthesis: Employed in academic and industrial R&D for constructing stereochemically defined molecular architectures.
• Chemical Reference Standard: Utilized as a high-purity standard for analytical method development and quality control in chiral separations.

Basic Information

Product Name	(S)-6,6'-Dibromo-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol,99%E.E.
CAS No.	1621066-74-7
Molecular Formula	C19H16Br2O2
Molecular Weight	436.14 g/mol
Synonyms	(S)-6,6'-Dibromospirobiindane-7,7'-diol; (S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[indene]-7,7'-diol; (S)-Spirobiindane-7,7'-diol, 6,6'-dibromo-; (S)-BINOL derivative, 6,6'-dibromo-; (S)-6,6'-Dibromo-BINOL derivative; (S)-6,6'-Dibromo-1,1'-bi-2,3-dihydro-1H-indene-7,7'-diol; (S)-6,6'-Dibromo-2,2',3,3'-tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol; (S)-6,6'-Dibromospirobiindane-7,7'-diol, 99% ee
EINECS	Contact for details

Quality Control

Our (S)-6,6'-Dibromo-2,2',3,3'-Tetrahydro-1,1'-Spirobi[1H-Indene]-7,7'-Diol,99%E.E. is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (EE) verification, to ensure it meets the high-purity standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% E.E.
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.