Description

7-Oxa-1-Azaspiro[4.4]Nonane (Hydrochloride) is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is valued for its unique spirocyclic structure, which is critical for imparting specific conformational and pharmacological properties in drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and psychiatric disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its constrained spirocyclic scaffold.
• Organic Synthesis: Serves as a versatile precursor for constructing complex nitrogen- and oxygen-containing heterocycles in academic and industrial R&D.
• Agrochemical Development: Potential application in the research and synthesis of new crop protection agents and pesticides.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique thermal or mechanical properties.

Basic Information

Item	Details
Product Name	7-Oxa-1-Azaspiro[4.4]Nonane (Hydrochloride)
CAS No.	1620569-18-7
Molecular Formula	C7H13NO • HCl
Molecular Weight	163.64 g/mol (Free base: 127.18 g/mol)
Synonyms	7-Oxa-1-azaspiro[4.4]nonane hydrochloride; 1-Aza-7-oxaspiro[4.4]nonane hydrochloride; 7-Oxa-1-azaspiro[4,4]nonane HCl; Spiro[4.4]nonane, 7-oxa-1-aza-, hydrochloride; 7-Oxa-1-azaspiro[4.4]nonane monohydrochloride; 1620569-18-7; Building block 1620569-18-7
EINECS	Contact for details

Quality Control

Our 7-Oxa-1-Azaspiro[4.4]Nonane (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.