Description

2-Amino-4-Trifluoromethanesulfinyl-Phenol is a specialized fluorinated phenolic compound featuring both amino and trifluoromethanesulfinyl functional groups. This unique molecular architecture makes it a valuable and versatile building block for advanced chemical synthesis, particularly in the development of novel active pharmaceutical ingredients and agrochemicals. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate fluorinated motifs for enhanced bioactivity or material properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially those targeting central nervous system (CNS) disorders, where fluorination can improve metabolic stability and blood-brain barrier penetration.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethanesulfinyl group can contribute to superior efficacy and environmental profile.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create novel ligands that can modulate the activity and selectivity of transition metal catalysts.
• Material Science Research: Employed in the synthesis of fluorinated polymers, liquid crystals, or organic electronic materials to impart specific thermal, optical, or electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-Amino-4-Trifluoromethanesulfinyl-Phenol
CAS No.	1616682-59-7
Molecular Formula	C7H6F3NO2S
Molecular Weight	225.19 g/mol
Synonyms	2-Amino-4-[(trifluoromethyl)sulfinyl]phenol; 4-(Trifluoromethylsulfinyl)benzene-1,3-diol; 2-Amino-4-(trifluoromethanesulfinyl)phenol; 1,3-Benzenediol, 2-amino-4-[(trifluoromethyl)sulfinyl]-; Phenol, 2-amino-4-[(trifluoromethyl)sulfinyl]-; 2-Amino-4-(trifluoromethylsulfinyl)phenol; 4-Trifluoromethanesulfinyl-2-aminophenol
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-Trifluoromethanesulfinyl-Phenol is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications and industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.