Description

5-Fluoro-1-Methyl-3-Nitropyridin-2(1H)-One is a high-value, fluorinated nitropyridinone derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific fluorine and nitro functional groups into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Research: Used in the development of new herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis for clients.

Basic Information

Item	Details
Product Name	5-Fluoro-1-Methyl-3-Nitropyridin-2(1H)-One
CAS No.	1616526-85-2
Molecular Formula	C6H5FN2O3
Molecular Weight	172.11 g/mol
Synonyms	5-Fluoro-1-methyl-3-nitro-1,2-dihydropyridin-2-one; 5-Fluoro-1-methyl-3-nitro-2(1H)-pyridinone; 3-Nitro-5-fluoro-1-methyl-2(1H)-pyridinone; 1-Methyl-5-fluoro-3-nitropyridin-2(1H)-one; 5-Fluoro-1-methyl-3-nitropyridin-2-one; 2(1H)-Pyridinone, 5-fluoro-1-methyl-3-nitro-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-Methyl-3-Nitropyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.