Description

6-Chloro-3-Methoxy-2-Nitropyridine is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its reactive nitro and chloro substituents.
• Material Science Research: Serves as a building block for creating functionalized pyridine derivatives used in ligands, catalysts, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific nitropyridine scaffolds.

Basic Information

Product Name	6-Chloro-3-Methoxy-2-Nitropyridine
CAS No.	1616526-81-8
Molecular Formula	C6H5ClN2O3
Molecular Weight	188.57 g/mol
Synonyms	2-Nitro-6-chloro-3-methoxypyridine; 3-Methoxy-6-chloro-2-nitropyridine; 6-Chloro-3-methoxy-2-nitropyridine; 2-Nitropyridine, 6-chloro-3-methoxy-; Pyridine, 6-chloro-3-methoxy-2-nitro-
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Methoxy-2-Nitropyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) with detailed chromatographic data are provided for all shipments, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.