Description

Spiro[9H-Fluorene-9,4'-Piperidine]-1'-Carboxylic Acid, 2,7-Dibromo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and halogenated fluorene structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and biotechnology industries for the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological disorders.
• Organic Light-Emitting Diode (OLED) Materials Research: Serves as a functionalized core structure for developing novel electron-transport or host materials due to its rigid, brominated fluorene moiety.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create sophisticated, sterically hindered ligands.
• Academic and Industrial R&D: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique thermal or optical properties.

Basic Information

Item	Details
Product Name	Spiro[9H-Fluorene-9,4'-Piperidine]-1'-Carboxylic Acid, 2,7-Dibromo-, 1,1-Dimethylethyl Ester
CAS No.	1616113-98-4
Molecular Formula	C23H23Br2NO2
Molecular Weight	513.25 g/mol
Synonyms	tert-Butyl 2,7-dibromospiro[fluorene-9,4'-piperidine]-1'-carboxylate; 1'-BOC-2,7-dibromospiro[fluorene-9,4'-piperidine]; 2,7-Dibromo-1'-(tert-butoxycarbonyl)spiro[fluorene-9,4'-piperidine]; Spiro(fluorene-9,4'-piperidine)-1'-carboxylic acid, 2,7-dibromo-, 1,1-dimethylethyl ester; BOC-2,7-Dibromospiro(fluorene-9,4'-piperidine); 1,1-Dimethylethyl 2,7-dibromospiro[9H-fluorene-9,4'-piperidine]-1'-carboxylate
EINECS	Contact for details

Quality Control

Our Spiro[9H-Fluorene-9,4'-Piperidine]-1'-Carboxylic Acid, 2,7-Dibromo-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be handled under inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.