Description

5-Bromo-1,2-Dihydrospiro[Indole-3,4-Oxane] Hcl is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indole-oxane scaffold. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and oncology-related drug discovery programs. It is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in synthesizing complex bioactive molecules.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its spirocyclic architecture.
• CNS Drug Discovery: Serves as a core scaffold for developing potential therapeutics for neurological and psychiatric disorders.
• Oncology Research: Employed in the synthesis of compounds for screening against cancer cell lines and specific molecular targets.
• Chemical Biology Probes: Utilized to create tool compounds for studying biological processes and protein function.
• Academic Research: Used in university and institutional labs for advanced synthetic organic chemistry and pharmacology studies.

Basic Information

Product Name	5-Bromo-1,2-Dihydrospiro[Indole-3,4-Oxane] Hydrochloride
CAS No.	1609266-05-8
Molecular Formula	C12H12BrNO • HCl
Molecular Weight	302.60 g/mol (Free base: 266.14 g/mol)
Synonyms	5-Bromo-1,2-dihydrospiro[indole-3,4'-oxane] hydrochloride; 5-Bromospiro[indoline-3,4'-oxane] hydrochloride; 5-Bromo-2,3-dihydro-1H-spiro[indole-3,4'-oxane] HCl; 1609266-05-8; Spiro[indoline-3,4'-oxane], 5-bromo-, hydrochloride; 5-Bromo-1,2-dihydrospiro[indole-3,4'-oxane] HCl salt
EINECS	Contact for details

Quality Control

Our 5-Bromo-1,2-Dihydrospiro[Indole-3,4-Oxane] Hcl is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.