Description

Azido-PEG4-β-D-Glucose is a specialized bifunctional linker molecule that combines a click chemistry-ready azide group with a PEGylated glucose moiety. This compound is engineered to facilitate the conjugation of biomolecules, offering enhanced solubility and biocompatibility for advanced research applications. It is primarily utilized by researchers and developers in the fields of bioconjugation, pharmaceutical development, and chemical biology for creating targeted probes and drug delivery systems.

Application

• Bioconjugation and Click Chemistry: Serves as a key reagent for azide-alkyne cycloaddition (CuAAC or SPAAC) reactions to label or functionalize biomolecules, peptides, and nanoparticles.
• Drug Delivery System Development: Used to synthesize prodrugs or targeted drug conjugates, leveraging the PEG spacer for improved pharmacokinetics and the glucose unit for potential tissue targeting.
• Chemical Biology Probes: Enables the creation of activity-based probes or imaging agents for studying glycosylation, metabolic pathways, and cellular processes.
• Glycopolymer and Material Science: Acts as a functional monomer or cross-linker for synthesizing smart hydrogels, biocompatible coatings, and glyconanomaterials.
• Antibody-Drug Conjugate (ADC) Research: Provides a versatile linker platform for constructing next-generation ADCs with tailored release profiles and stability.
• Diagnostic Reagent Synthesis: Employed in the development of diagnostic assays and biosensors where specific biomolecular attachment is required.

Basic Information

Product Name	Azido-PEG4-β-D-Glucose
CAS No.	1609083-15-9
Molecular Formula	C19H35N3O11
Molecular Weight	481.5 g/mol
Synonyms	1-Azido-3,6,9,12-tetraoxapentadecan-15-yl β-D-glucopyranoside; Azido-PEG4-β-D-glucoside; N3-PEG4-Glucose; β-D-Glucose, 1-[2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethyl] glycoside; PEG4-Azide-Glucose; Azido tetraethylene glycol β-D-glucoside; Azido-PEG4-Glc
EINECS	Contact for details

Quality Control

Our Azido-PEG4-β-D-Glucose is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.