Description

3-Pyridinecarboxylic Acid, 4,6-Dichloro-5-Fluoro-, Methyl Ester is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which is essential for introducing specific pharmacophores and modifying the physicochemical properties of target molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides, where the fluorine and chlorine substituents enhance biological activity and environmental stability.
• Material Science: Serves as a precursor for functionalized ligands and monomers in the creation of specialty polymers and advanced organic electronic materials.
• Chemical Synthesis: Employed as a versatile reagent for introducing the 4,6-dichloro-5-fluoro-pyridine moiety into more complex molecular architectures via cross-coupling or nucleophilic substitution reactions.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 4,6-Dichloro-5-Fluoro-, Methyl Ester
CAS No.	1588977-21-2
Molecular Formula	C8H4Cl2FNO2
Molecular Weight	240.03 g/mol
Synonyms	Methyl 4,6-dichloro-5-fluoronicotinate; 4,6-Dichloro-5-fluoro-3-pyridinecarboxylic acid methyl ester; 4,6-Dichloro-5-fluoronicotinic acid methyl ester; Methyl 4,6-dichloro-5-fluoropyridine-3-carboxylate; 3-Carbomethoxy-4,6-dichloro-5-fluoropyridine; Nicotinic acid, 4,6-dichloro-5-fluoro-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 4,6-Dichloro-5-Fluoro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurity profile, and physical characteristics are provided with every shipment to guarantee batch-to-batch consistency and traceability for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The compound may be moisture-sensitive; ensure containers are sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.