Description

2-Thia-8-Azaspiro[4.5]Decane 2,2-Dioxide Hydrochloride (Wx102737S1) is a high-purity, heterocyclic building block and pharmaceutical intermediate of significant synthetic utility. This compound is valued for its unique spirocyclic structure, which serves as a critical scaffold in modern medicinal chemistry for developing novel therapeutic agents. It is primarily sought after by research institutions and pharmaceutical companies engaged in the discovery and synthesis of new active pharmaceutical ingredients (APIs), particularly within central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex molecules for agrochemical and material science applications.
• Chemical Biology Probes: Utilized in the development of specialized probes and ligands for studying enzyme mechanisms and biological pathways.
• Process Chemistry Development: Employed in the scale-up and optimization of synthetic routes for potential commercial drug manufacturing.

Basic Information

Product Name	2-Thia-8-Azaspiro[4.5]Decane 2,2-Dioxide Hydrochloride (Wx102737S1)
CAS No.	1588960-00-2
Molecular Formula	C8H16ClNO2S
Molecular Weight	225.74 g/mol
Synonyms	8-Thia-2-azaspiro[4.5]decane 8,8-dioxide hydrochloride; 2-Thia-8-azaspiro[4.5]decane 2,2-dioxide HCl; Spiro[4.5]decane-8-sulfonamide, 2-aza-, hydrochloride; Wx-102737S1; 1588960-00-2; 2-Thia-8-azaspiro[4.5]decane-2,2-dioxide monohydrochloride; 8-Aza-2-thiaspiro[4.5]decane 2,2-dioxide hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Thia-8-Azaspiro[4.5]Decane 2,2-Dioxide Hydrochloride is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP requirements for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.