Description

6-Aminonicotinaldehyde Hydrochloride is a high-purity organic building block essential for advanced pharmaceutical and agrochemical synthesis. This compound serves as a versatile precursor for constructing complex heterocyclic scaffolds, enabling the development of novel active ingredients. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nicotinamide derivatives, kinase inhibitors, and other nitrogen-containing heterocycles with potential therapeutic activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive aldehyde and amine functional groups.
• Chemical Biology & Proteomics: Acts as a versatile linker or labeling reagent for bioconjugation and probe development due to its amine-reactive properties.
• Material Science: Employed in the synthesis of functionalized ligands for metal-organic frameworks (MOFs) and coordination polymers.
• Academic & Contract Research: Serves as a fundamental building block in medicinal chemistry laboratories for library synthesis and structure-activity relationship (SAR) studies.

Basic Information

Item	Detail
Product Name	6-Aminonicotinaldehyde Hydrochloride
CAS No.	1588441-31-9
Molecular Formula	C6H7N2O·HCl
Molecular Weight	158.59 g/mol
Synonyms	6-Amino-3-pyridinecarboxaldehyde hydrochloride; 6-Aminopyridine-3-carboxaldehyde hydrochloride; 3-Pyridinecarboxaldehyde, 6-amino-, hydrochloride; 6-Amino-3-formylpyridine hydrochloride; 6-Aminonicotinaldehyde HCl; 6-Amino-3-pyridylaldehyde hydrochloride; 6-Aminonicotinic aldehyde hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Aminonicotinaldehyde Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.