Description

7-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride is a high-purity, pharmaceutically relevant building block and intermediate. This compound is valued for its rigid, spirocyclic diaza structure, which is crucial for modulating the physicochemical and biological properties of drug candidates. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the research and synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its constrained, three-dimensional geometry.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery programs.
• Chemical Biology Probe Development: Serves as a scaffold for developing tool compounds to study biological pathways and protein function.
• Process Chemistry: Used in the development and scale-up of robust synthetic routes for candidate drugs under Good Manufacturing Practice (GMP) guidelines.

Basic Information

Product Name	7-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride
CAS No.	1588441-26-2
Molecular Formula	C9H18N2·2HCl
Molecular Weight	239.18 g/mol
Synonyms	7-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride; 2,7-Diazaspiro[3.5]nonane, 7-methyl-, dihydrochloride; 7-Methyl-2,7-diazaspiro[3.5]nonane hydrochloride (1:2); 7-Methyl-2,7-diazaspiro[3.5]nonane, 2HCl; 7-Methyl-2,7-diazaspiro[3.5]nonane HCl salt; 1588441-26-2; 7-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride salt
EINECS	Contact for details

Quality Control

Our 7-Methyl-2,7-diazaspiro[3.5]nonane dihydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each lot, supporting development under quality-by-design (QbD) principles and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions (e.g., nitrogen atmosphere) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.