Description

Picolyl-Azide-Acid CAS NO 1581292-61-6 is a specialized bifunctional organic compound featuring both an azide group and a carboxylic acid moiety on a picolyl scaffold. This unique structure makes it a highly valuable click chemistry reagent and a versatile molecular building block for the synthesis of complex architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications ranging from bioconjugation to polymer functionalization.

Application

• Click Chemistry Reagent: Used in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for the efficient and selective conjugation of molecules.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for creating targeted bioconjugates.
• Bioconjugation & Probe Development: Enables the labeling of proteins, antibodies, and other biomolecules with fluorescent dyes, affinity tags, or therapeutic payloads.
• Polymer & Materials Science: Used to functionalize polymers, dendrimers, and surfaces, introducing azide handles for further modification to create smart materials.
• Agrochemical Research: Employed in the design and synthesis of novel crop protection agents and herbicides.
• Chemical Biology Tool: Facilitates the study of biological processes through the creation of activity-based probes and affinity-based protein profiling reagents.

Basic Information

Product Name	Picolyl-Azide-Acid
CAS No.	1581292-61-6
Molecular Formula	C7H6N4O2
Molecular Weight	178.15 g/mol
Synonyms	2-(Azidomethyl)isonicotinic Acid; 2-(Azidomethyl)pyridine-4-carboxylic Acid; 4-Pyridinecarboxylic acid, 2-(azidomethyl)-; Picolyl Azide Carboxylic Acid; Azido-Picolyl-Acid; Click Chemistry Acid Reagent
EINECS	Contact for details

Quality Control

Our Picolyl-Azide-Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.