Description

7-Fluoro-1,6-Naphthyridine-2-Carboxylic Acid is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its dual functionality, combining a carboxylic acid group for derivatization with a fluorine-substituted naphthyridine scaffold, enabling precise modulation of molecular properties. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients, where its unique structure can impart improved metabolic stability, bioavailability, and target binding affinity.

Application

• Key synthetic intermediate in the research and development of novel pharmaceutical candidates, particularly in kinase inhibitor and antiviral drug discovery.
• Building block for constructing complex agrochemical molecules, such as herbicides and fungicides, leveraging the fluorine atom for enhanced activity.
• Precursor in material science for the synthesis of specialty ligands and coordination complexes used in catalysis.
• Versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Starting material for the preparation of fluorinated analogs of bioactive compounds to study the effects of fluorine substitution.
• Used in academic research for exploring new synthetic methodologies involving fluorinated heterocycles.

Basic Information

Product Name	7-Fluoro-1,6-Naphthyridine-2-Carboxylic Acid
CAS No.	1574395-52-0
Molecular Formula	C9H5FN2O2
Molecular Weight	192.15 g/mol
Synonyms	7-Fluoro-1,6-naphthyridine-2-carboxylic acid; 2-Carboxy-7-fluoro-1,6-naphthyridine; 7-Fluoro-1,6-naphthyridine-2-carboxylic acid; 1,6-Naphthyridine-2-carboxylic acid, 7-fluoro-; 7-Fluoronaphthyridine-2-carboxylic acid; 7-F-1,6-Naph-2-COOH; 7-Fluoro-2-carboxy-1,6-naphthyridine
EINECS	Contact for details

Quality Control

Our 7-Fluoro-1,6-Naphthyridine-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark place to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.