Description

5-Amino-4-Fluoro-2-Methyl-Benzoic Acid Methyl Ester is a high-purity, multifunctional fluorinated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and fluorine substituents, makes it an essential intermediate for creating complex molecules with tailored biological and physical properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the fluorine atom enhances bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic components in electronic materials, improving charge transport and thermal stability.
• Dye & Pigment Manufacturing: Intermediate for producing specialized fluorinated dyes and pigments with enhanced color fastness and unique optical properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and library synthesis.
• Peptide Mimetics & Bio-conjugation: The ester and amino functionalities allow for its use in creating peptide analogs and for bio-conjugation linker chemistry.

Basic Information

Product Name	5-Amino-4-Fluoro-2-Methyl-Benzoic Acid Methyl Ester
CAS No.	1567119-84-9
Molecular Formula	C9H10FNO2
Molecular Weight	183.18 g/mol
Synonyms	Methyl 5-Amino-4-Fluoro-2-Methylbenzoate; 4-Fluoro-5-Amino-2-Methylbenzoic Acid Methyl Ester; 2-Methyl-5-Amino-4-Fluorobenzoic Acid Methyl Ester; Benzoic acid, 5-amino-4-fluoro-2-methyl-, methyl ester; Methyl 4-fluoro-5-amino-o-toluate
EINECS	Contact for details

Quality Control

Every batch of 5-Amino-4-Fluoro-2-Methyl-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical testing including HPLC, GC, NMR, and MS. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. Our quality commitment ensures the material is suitable for demanding applications in cGMP-compliant pharmaceutical synthesis and other regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.