Description

Methyl 5-tert-Butyl-1,3,4-Oxadiazole-2-Carboxylate is a high-value heterocyclic building block and synthetic intermediate of significant interest in advanced organic synthesis. Its core value lies in its versatile oxadiazole scaffold, which is crucial for imparting specific biological and physicochemical properties to target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Active Ingredient Development: Used to construct novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the 1,3,4-oxadiazole ring system.
• Material Science Research: Acts as a monomer or functional additive in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a tagging reagent or a scaffold for designing enzyme inhibitors and molecular probes in biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex heterocyclic architectures for client-specific applications.

Basic Information

Product Name	Methyl 5-tert-Butyl-1,3,4-Oxadiazole-2-Carboxylate
CAS No.	1565976-13-7
Molecular Formula	C8H12N2O3
Molecular Weight	184.19 g/mol
Synonyms	5-tert-Butyl-1,3,4-oxadiazole-2-carboxylic acid methyl ester; Methyl 5-(tert-butyl)-1,3,4-oxadiazole-2-carboxylate; 2-Methoxycarbonyl-5-tert-butyl-1,3,4-oxadiazole; 1,3,4-Oxadiazole-2-carboxylic acid, 5-(1,1-dimethylethyl)-, methyl ester; Methyl 5-(1,1-dimethylethyl)-1,3,4-oxadiazole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 5-tert-Butyl-1,3,4-Oxadiazole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.