Description

Methyl 3-Bromo-4-Fluoro-6-Methylbenzoate is a high-purity, multi-functional aromatic ester building block essential for advanced organic synthesis. Its value lies in the strategic positioning of halogen substituents (bromo and fluoro) and the methyl ester group, which enable precise molecular modifications and the construction of complex pharmacophores. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine and bromine atoms enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Synthesis: Serves as a building block for creating advanced organic electronic materials and liquid crystal compounds.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Group Transformation: The methyl ester group can be hydrolyzed to the corresponding acid, reduced to the alcohol, or converted to amides and other derivatives.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for imaging and diagnostic applications.

Basic Information

Item	Details
Product Name	Methyl 3-Bromo-4-Fluoro-6-Methylbenzoate
CAS No.	1564624-36-7
Molecular Formula	C9H8BrFO2
Molecular Weight	247.06 g/mol
Synonyms	3-Bromo-4-fluoro-6-methylbenzoic acid methyl ester; Methyl 3-bromo-4-fluoro-6-methylbenzoate; Benzoic acid, 3-bromo-4-fluoro-6-methyl-, methyl ester; 1564624-36-7; Methyl 3-bromo-4-fluoro-o-toluate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-4-Fluoro-6-Methylbenzoate adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and GC for residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.