Description

Ethyl (2E)-3-(2-Fluoropyridin-3-Yl)Prop-2-Enoate is a high-purity fluorinated pyridine derivative, a crucial building block in modern organic synthesis. Its value lies in its role as a versatile intermediate for constructing complex molecules with enhanced biological activity and specific physicochemical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, where it serves as a key precursor for active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and insecticides, leveraging the fluorine atom for improved efficacy and environmental profile.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential intermediate for synthesizing specialty chemicals, ligands, or functionalized materials requiring a fluoropyridine moiety.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production of client molecules.

Basic Information

Item	Details
Product Name	Ethyl (2E)-3-(2-Fluoropyridin-3-Yl)Prop-2-Enoate
CAS No.	1563741-43-4
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	(2E)-Ethyl 3-(2-Fluoro-3-pyridinyl)-2-propenoate; Ethyl (E)-3-(2-Fluoropyridin-3-yl)acrylate; 2-Fluoro-3-pyridylacrylic Acid Ethyl Ester; 3-(2-Fluoropyridin-3-yl)acrylic Acid Ethyl Ester; (E)-Ethyl 3-(2-fluoropyridin-3-yl)acrylate; 1563741-43-4; 2-Propenoic acid, 3-(2-fluoro-3-pyridinyl)-, ethyl ester, (2E)-
EINECS	Contact for details

Quality Control

Our Ethyl (2E)-3-(2-Fluoropyridin-3-Yl)Prop-2-Enoate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support development and commercial projects with material suitable for research use and can supply under cGMP standards for advanced clinical phases upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.