Description

Methyl 2-Bromo-4-Cyclopropylbenzoate is a high-purity, advanced pharmaceutical intermediate characterized by its brominated cyclopropyl benzoate structure. This compound is critical for enabling complex molecular transformations in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds and process optimization.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides with novel modes of action.
• Material Science: Used in the research and development of advanced organic materials, including liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: An essential substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) for constructing biaryl systems.
• Chemical Synthesis: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating chemical libraries.
• Fine Chemical Production: Acts as a versatile intermediate for manufacturing specialty dyes, pigments, and performance chemicals.

Basic Information

Product Name	Methyl 2-Bromo-4-Cyclopropylbenzoate
CAS No.	1563534-75-7
Molecular Formula	C11H11BrO2
Molecular Weight	255.11 g/mol
Synonyms	Methyl 2-bromo-4-cyclopropylbenzoate; 2-Bromo-4-cyclopropylbenzoic acid methyl ester; Benzoic acid, 2-bromo-4-cyclopropyl-, methyl ester; Methyl o-bromo-p-cyclopropylbenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2-Bromo-4-Cyclopropylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.