Description

3-Bromo-2-Propoxy-Pyridin-4-Ylamine is a high-purity pyridine derivative building block, essential for advanced organic synthesis and pharmaceutical research. Its unique halogenated and alkoxy-substituted structure makes it a versatile intermediate for constructing complex molecules with targeted biological activity. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized organic materials, such as liquid crystals or organic semiconductors, where its substituents can tune electronic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	3-Bromo-2-Propoxy-Pyridin-4-Ylamine
CAS No.	1563530-65-3
Molecular Formula	C8H11BrN2O
Molecular Weight	231.09 g/mol
Synonyms	4-Amino-3-bromo-2-propoxy-pyridine; 3-Bromo-2-propoxy-4-pyridinamine; 4-Pyridinamine, 3-bromo-2-propoxy-; 2-Propoxy-3-bromopyridin-4-amine; 3-Bromo-2-propoxy-4-aminopyridine; 4-Amino-3-bromo-2-propoxy-pyridine (primary IUPAC); 3-Bromo-2-(propoxy)pyridin-4-amine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Propoxy-Pyridin-4-Ylamine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP (current Good Manufacturing Practice) requirements for advanced intermediate production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.