Description

2-Amino-4-(n-Boc-Piperidin-3-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine amine group. This compound is critically important for the research and development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and fine chemical synthesis companies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and CNS-targeting molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a critical starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring a protected amino-pyridine scaffold.
• Academic Research: Used in university and institutional labs for exploring new synthetic methodologies and biological targets.

Basic Information

Product Name	2-Amino-4-(n-Boc-Piperidin-3-Yl)Pyridine
CAS No.	1563530-10-8
Molecular Formula	C15H23N3O2
Molecular Weight	277.36 g/mol
Synonyms	2-Amino-4-(3-Boc-piperidin-4-yl)pyridine; 4-(3-[(tert-Butoxycarbonyl)amino]piperidin-1-yl)pyridin-2-amine; tert-Butyl 3-(2-aminopyridin-4-yl)piperidine-1-carboxylate; 2-Amino-4-(1-Boc-3-piperidyl)pyridine; 2-Amino-4-(N-Boc-piperidin-3-yl)pyridine; 1-Boc-3-(2-Aminopyridin-4-yl)piperidine
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-(n-Boc-Piperidin-3-Yl)Pyridine is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced analytical techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.