Description

Cyanine5.5 Azide is a near-infrared fluorescent dye functionalized with a reactive azide group for bioorthogonal click chemistry. This compound is essential for researchers and developers requiring high-sensitivity, deep-tissue imaging and biomolecule conjugation with minimal background interference. It is primarily used by professionals in the life sciences, pharmaceutical development, and diagnostic industries for labeling proteins, antibodies, nucleic acids, and other biomolecules.

Application

• Bioconjugation and Biomolecule Labeling: Site-specific labeling of proteins, peptides, antibodies, and oligonucleotides via copper-free click chemistry with alkyne-modified targets.
• In Vivo and In Vitro Imaging: A critical reagent for near-infrared fluorescence (NIRF) imaging applications, enabling deep-tissue penetration and reduced autofluorescence.
• Diagnostic Probe Development: Used in the synthesis of targeted imaging probes and contrast agents for preclinical research and diagnostic assay development.
• Flow Cytometry and Microscopy: Fluorescent tag for cell surface labeling, intracellular tracking, and high-resolution cellular imaging studies.
• Material Science Functionalization: Modification of nanoparticles, polymers, and surfaces with fluorescent properties for sensing and tracking applications.
• Drug Delivery Research: Conjugation to drug carriers or therapeutic molecules to visualize distribution, uptake, and pharmacokinetics.

Basic Information

Product Name	Cyanine5.5 Azide
CAS No.	1557149-65-1
Molecular Formula	C44H51N6O3+
Molecular Weight	711.93 g/mol
Synonyms	Cy5.5 Azide; Sulfo-Cyanine5.5 Azide; Cy5.5 N3; NIR Dye Azide; 2-((1E,3E)-5-(1-(6-Azidohexyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium-5-sulfonate; Cyanine 5.5 Azide; Azide-functionalized Cy5.5; Near-infrared fluorescent azide
EINECS	Contact for details

Quality Control

Our Cyanine5.5 Azide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring compliance with research-grade specifications and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. The product is hygroscopic (moisture-sensitive). For long-term storage, keep under inert atmosphere. Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Extinction Coefficient	≥ 190,000 cm-1M-1 (at λmax)
Solubility	Soluble in DMSO, DMF, water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.