Description

Methyl 3-(4-Bromophenyl)-3-Hydroxycyclobutanecarboxylate is a high-purity, synthetically valuable cyclobutane derivative, serving as a crucial chiral building block in advanced organic synthesis. Its unique structure, featuring a brominated aromatic ring and a functionalized cyclobutane core, makes it indispensable for constructing complex molecular architectures with precise stereochemistry. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in areas requiring constrained, three-dimensional scaffolds.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the cyclobutane ring can impart favorable biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or building block for specialty polymers with unique thermal or mechanical properties.
• Academic & Industrial R&D: Employed in methodological studies and process chemistry for constructing complex, strained ring systems.

Basic Information

Product Name	Methyl 3-(4-Bromophenyl)-3-Hydroxycyclobutanecarboxylate
CAS No.	1555708-89-8
Molecular Formula	C12H13BrO3
Molecular Weight	285.14 g/mol
Synonyms	Methyl 3-hydroxy-3-(4-bromophenyl)cyclobutanecarboxylate; 3-(4-Bromophenyl)-3-hydroxycyclobutanecarboxylic acid methyl ester; 3-Hydroxy-3-(4-bromophenyl)cyclobutanecarboxylic Acid Methyl Ester; (3-Hydroxy-3-(4-bromophenyl)cyclobutyl)methyl carboxylate; Methyl 3-(p-bromophenyl)-3-hydroxycyclobutanecarboxylate; 1555708-89-8; Cyclobutanecarboxylic acid, 3-(4-bromophenyl)-3-hydroxy-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 3-(4-Bromophenyl)-3-Hydroxycyclobutanecarboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.