Description

tert-Butyl2-(4-tert-Butylphenyl)-3-Oxo-1,4,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the spirocyclic triaza class of compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with potential therapeutic applications. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially those with spirocyclic or constrained heterocyclic architectures.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop compounds with improved potency and selectivity.
• API Development: Employed in the scalable production of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical trial materials.
• Chemical Biology Probes: Acts as a scaffold for creating specialized probes to study enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical R&D and production.

Basic Information

Product Name	tert-Butyl2-(4-tert-Butylphenyl)-3-Oxo-1,4,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate
CAS No.	1552151-99-1
Molecular Formula	C22H31N3O3
Molecular Weight	385.50 g/mol
Synonyms	tert-Butyl 2-(4-tert-butylphenyl)-3-oxo-1,4,8-triazaspiro[4.5]dec-1-ene-8-carboxylate; 1,4,8-Triazaspiro[4.5]dec-1-ene-8-carboxylic acid, 2-(4-(1,1-dimethylethyl)phenyl)-3-oxo-, 1,1-dimethylethyl ester; 8-Boc-2-(4-tert-butylphenyl)-3-oxo-1,4,8-triazaspiro[4.5]dec-1-ene; Spirocyclic Triaza Intermediate 1552151-99-1
EINECS	Contact for details

Quality Control

Our tert-Butyl2-(4-tert-Butylphenyl)-3-Oxo-1,4,8-Triazaspiro[4.5]Dec-1-Ene-8-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with ICH guidelines and supports cGMP-compliant pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, open flames, and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.