Description

n-(2,2-Dimethylpropyl)-n-Methylcarbamoyl Chloride CAS NO 1543028-41-6 is a specialized carbamoyl chloride derivative, a crucial building block in advanced organic synthesis. Its primary value lies in its role as a reactive intermediate for introducing the N-(2,2-dimethylpropyl)-N-methylcarbamoyl moiety into target molecules, enabling the development of novel compounds with tailored properties. This high-purity reagent is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly in medicinal chemistry programs and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the bulky tert-butyl-like side chain can influence bioactivity and stability.
• Medicinal Chemistry & Drug Discovery: A valuable reagent for constructing compound libraries and exploring structure-activity relationships (SAR) in lead optimization.
• Peptide Mimetics & Modifications: Employed to introduce specific, sterically hindered carbamate protecting groups or functional motifs into peptide analogs and biomolecules.
• Material Science Research: Serves as a monomer or functionalization agent in the synthesis of specialized polymers and functional materials.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke organic compounds for client projects.

Basic Information

Product Name	n-(2,2-Dimethylpropyl)-n-Methylcarbamoyl Chloride
CAS No.	1543028-41-6
Molecular Formula	C8H16ClNO
Molecular Weight	177.67 g/mol
Synonyms	N-(Neopentyl)-N-methylcarbamoyl Chloride; N-Methyl-N-(2,2-dimethylpropyl)carbamoyl Chloride; Carbamic chloride, N-(2,2-dimethylpropyl)-N-methyl-; N-(2,2-Dimethylpropyl)-N-methylcarbamoyl Chloride; Neopentyl(methyl)carbamoyl Chloride; 1,1-Dimethylpropyl(methyl)carbamoyl Chloride; tert-Butyl(methyl)carbamoyl Chloride (related structural isomer); (2,2-Dimethylpropyl)(methyl)carbamic Chloride
EINECS	Contact for details

Quality Control

Our n-(2,2-Dimethylpropyl)-n-Methylcarbamoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.