Description

1,3-Cyclobutanedicarboxylic Acid, 2,4-Diphenyl-, 1-(1-Naphthalenyl) Ester, (1β,2R,3α,4R)- is a high-purity, stereochemically defined advanced pharmaceutical intermediate (API intermediate) with a complex polycyclic structure. This compound matters for its role as a critical building block in the synthesis of novel, high-value active pharmaceutical ingredients, enabling precise molecular architecture. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries working on next-generation therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new chemical entities (NCEs), particularly for complex target molecules.
• Asymmetric Synthesis: Utilized in stereoselective synthesis routes to construct molecules with specific three-dimensional configurations critical for biological activity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to develop potent and selective drug candidates.
• Process Chemistry Development: Used for scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• High-Value Fine Chemical Production: Acts as a precursor in the manufacture of specialized fine chemicals for advanced material science applications.

Basic Information

Product Name	1,3-Cyclobutanedicarboxylic Acid, 2,4-Diphenyl-, 1-(1-Naphthalenyl) Ester, (1β,2R,3α,4R)-
CAS No.	1541209-75-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(1β,2R,3α,4R)-1-(Naphthalen-1-yl) 2,4-diphenylcyclobutane-1,3-dicarboxylate; 2,4-Diphenyl-1,3-cyclobutanedicarboxylic Acid 1-(1-Naphthyl) Ester; 1-Naphthyl 2,4-diphenylcyclobutane-1,3-dicarboxylate; (1R,2S,3S,4R)-1-(1-Naphthyl) 2,4-diphenylcyclobutane-1,3-dicarboxylate; Stereoisomer of 1,3-Cyclobutanedicarboxylic Acid, 2,4-Diphenyl-, 1-(1-Naphthalenyl) Ester; API Intermediate 1541209-75-9; Chiral Cyclobutane Ester Derivative
EINECS	Contact for details

Quality Control

Our 1,3-Cyclobutanedicarboxylic Acid, 2,4-Diphenyl-, 1-(1-Naphthalenyl) Ester, (1β,2R,3α,4R)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure high chemical and stereochemical purity suitable for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your regulatory and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed in a dry, inert environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.