Description

5-Azaspiro[2.3]Hexane Hydrochloride (Wxc08346S1) is a high-purity, advanced pharmaceutical intermediate and building block with the CAS number 1536169-63-7. This spirocyclic amine derivative is valued for its unique three-dimensional structure, which is critical for modulating the physicochemical and biological properties of novel drug candidates. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the research and synthesis of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore novel chemical space and improve drug-like properties.
• Process Chemistry & Scale-Up: Serves as a starting material for the development of robust, scalable synthetic routes under GMP conditions.
• Proteolysis Targeting Chimera (PROTAC) Development: Utilized as a component in the linker or ligand design for targeted protein degradation therapeutics.
• Agrochemical Research: Employed in the discovery of new crop protection agents and pesticides due to its spirocyclic scaffold.
• Chemical Biology Probes: Incorporated into molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	5-Azaspiro[2.3]Hexane Hydrochloride (Wxc08346S1)
CAS No.	1536169-63-7
Molecular Formula	C6H11N·HCl
Molecular Weight	133.62 g/mol
Synonyms	5-Azaspiro[2.3]hexane, hydrochloride; 5-Azaspiro[2.3]hexane HCl; 1-Azaspiro[2.3]hexane hydrochloride; Spiro[cyclopropane-1,2'-pyrrolidine] hydrochloride; Azaspirohexane hydrochloride; WXC08346S1; 1536169-63-7
EINECS	Contact for details

Quality Control

Our 5-Azaspiro[2.3]Hexane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting compliance with agreed specifications. Our quality commitment supports applications from early-stage research through to pre-clinical and clinical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.