Description

2-Pyrrolidinemethanol, α-[(Methyldiphenylsilyl)Methyl]-, (αr,2R)- is a high-value, chiral organosilicon compound featuring a pyrrolidine-methanol backbone. This compound matters as a sophisticated chiral building block and ligand, crucial for asymmetric synthesis in advanced pharmaceutical and fine chemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• As a chiral ligand or catalyst in asymmetric synthesis, including hydrogenation and carbon-carbon bond-forming reactions.
• As a key intermediate in pharmaceutical research for the development of novel therapeutic agents.
• In the synthesis of complex natural products and biologically active molecules requiring precise stereochemical control.
• For use in methodology development within academic and industrial organic chemistry laboratories.
• As a building block for creating specialized organosilicon compounds with tailored properties.
• In process chemistry for the scale-up and optimization of synthetic routes to chiral targets.

Basic Information

Product Name	2-Pyrrolidinemethanol, α-[(Methyldiphenylsilyl)Methyl]-, (αr,2R)-
CAS No.	1528733-64-3
Molecular Formula	C19H25NOSi
Molecular Weight	311.50 g/mol
Synonyms	(αR,2R)-α-[(Methyldiphenylsilyl)methyl]-2-pyrrolidinemethanol; (2R)-1-[(αR)-Methyldiphenylsilyl]methyl-2-pyrrolidinemethanol; (R,R)-Methyldiphenylsilylmethyl Pyrrolidinemethanol; Chiral Diphenylsilyl Pyrrolidine Methanol; Organosilicon Chiral Auxiliary; CAS 1528733-64-3
EINECS	Contact for details

Quality Control

Our 2-Pyrrolidinemethanol, α-[(Methyldiphenylsilyl)Methyl]-, (αr,2R)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including chiral purity analysis by HPLC, to ensure high chemical and enantiomeric purity suitable for demanding research applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from strong alkali and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.