Description

{Spiro[2.3]Hexan-5-Yl}Methanamine Hydrochloride is a high-purity, specialized organic building block featuring a unique spirocyclic amine structure. This compound is a critical intermediate in modern pharmaceutical research and development, particularly valued for its rigid, three-dimensional scaffold which can impart desirable pharmacokinetic properties to drug candidates. It is primarily sought after by medicinal chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel small-molecule drug candidates targeting central nervous system (CNS) disorders, infectious diseases, and metabolic conditions.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and improve drug-like properties.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in the scale-up and route development for potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes and tool compounds for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the discovery of new crop protection agents and pesticides, leveraging its unique spirocyclic structure.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) settings for fundamental organic synthesis and methodological studies.

Basic Information

Item	Detail
Product Name	{Spiro[2.3]Hexan-5-Yl}Methanamine Hydrochloride
CAS No.	1528564-50-2
Molecular Formula	C8H16ClN
Molecular Weight	161.67 g/mol
Synonyms	Spiro[2.3]hexan-5-ylmethanamine hydrochloride; 5-(Aminomethyl)spiro[2.3]hexane hydrochloride; (Spiro[2.3]hexan-5-yl)methylamine hydrochloride; 1-Azaspiro[2.3]hexane-5-methanamine hydrochloride (incorrect but common misnomer); Aminomethylspiro[2.3]hexane HCl; CAS 1528564-50-2; Spirohexylmethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our {Spiro[2.3]Hexan-5-Yl}Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.