Description

2,6-Diazaspiro[3.3]heptane, 2-Methyl-, Ethanedioate (1:?) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic diaza scaffold. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in the development of small molecule therapeutics. The material, identified by CAS NO 1527515-86-1, is supplied under stringent quality control to ensure batch-to-batch consistency for critical R&D and scale-up processes.

Application

This specialized intermediate is designed for advanced synthetic applications, primarily within pharmaceutical research and development.

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry & Drug Discovery: Used as a privileged scaffold or building block for constructing novel compound libraries for high-throughput screening (HTS).
• CNS Drug Development: Its spirocyclic diaza structure is particularly relevant for creating molecules that interact with neurological receptors and enzymes.
• Antiviral Agent Synthesis: Employed in the research and development of new antiviral compounds.
• Chemical Biology & Proteolysis Targeting Chimeras (PROTACs): Utilized as a component in the design of bifunctional molecules for targeted protein degradation.
• Process Chemistry & Scale-Up: Supports route scouting, optimization, and pilot-scale manufacturing of developmental drugs.

Basic Information

Product Name	2,6-Diazaspiro[3.3]heptane, 2-Methyl-, Ethanedioate (1:?)
CAS No.	1527515-86-1
Molecular Formula	C8H12N2O4 (Base salt form to be confirmed)
Molecular Weight	Contact for details
Synonyms	2-Methyl-2,6-diazaspiro[3.3]heptane oxalate; 2-Methyl-2,6-diazaspiro[3.3]heptane ethanedioate; 2-Methyl-2,6-diazaspiro[3.3]heptane hemioxalate; 2-Methyl-2,6-diazaspiro[3.3]heptane (oxalate); 2-Methyl-2,6-diazaspiro[3.3]heptane, oxalic acid salt; 2-Methyl-2,6-diazaspiro[3.3]heptane hydrogen oxalate; Spirocyclic diaza building block
EINECS	Contact for details

Quality Control

Our 2,6-Diazaspiro[3.3]heptane, 2-Methyl-, Ethanedioate (1:?) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements for preclinical and clinical-stage materials.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic (moisture-sensitive) nature, the container should be stored in a cool, dry place, ideally under an inert atmosphere such as nitrogen or argon after opening. Recommended long-term storage temperature is 2-8°C (refrigerated) or -20°C for extended periods. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay (Titration)	Contact for details
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.