Description

Ethyl 2-Oxaspiro[3.3]heptane-6-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic oxetane scaffold. This compound is valued for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with improved metabolic stability and pharmacokinetic properties. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of small-molecule therapeutics, particularly for oncology, antiviral, and central nervous system (CNS) targets.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex molecules in drug discovery and development pipelines.
• Medicinal Chemistry Research: Used to introduce the sterically constrained and polarity-modifying 2-oxaspiro[3.3]heptane moiety into lead compounds.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker component due to its rigid three-dimensional structure.
• Chemical Biology Probes: Employed in the synthesis of tool compounds for target identification and validation studies.
• Agrochemical Research: Investigated as an intermediate for novel active ingredients requiring specific spatial orientation.
• Material Science: Explored as a monomer or cross-linker for specialty polymers with tailored physical properties.

Basic Information

Product Name	Ethyl 2-Oxaspiro[3.3]heptane-6-carboxylate
CAS No.	1523572-08-8
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	6-(Ethoxycarbonyl)-2-oxaspiro[3.3]heptane; Ethyl 6-carboxy-2-oxaspiro[3.3]heptane-6-carboxylate; 2-Oxaspiro[3.3]heptane-6-carboxylic acid, ethyl ester; Spiro[2.2]pentane-1-carboxylic acid, 3-oxa-, ethyl ester (related); Oxetane-spirocyclopropane carboxylate ester
EINECS	Contact for details

Quality Control

Our Ethyl 2-Oxaspiro[3.3]heptane-6-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.