Description

2-(Bromomethyl)-3-Fluoropyridine Hcl is a high-purity halogenated pyridine derivative, a crucial building block in advanced organic synthesis. Its molecular structure, featuring both bromomethyl and fluoro substituents, makes it an exceptionally versatile intermediate for constructing complex pharmacophores and agrochemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of functionalized polymers and advanced organic materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	2-(Bromomethyl)-3-Fluoropyridine Hcl
CAS No.	1523571-83-6
Molecular Formula	C6H6BrFN•HCl
Molecular Weight	226.48 g/mol (Free base: 190.02 g/mol)
Synonyms	3-Fluoro-2-(bromomethyl)pyridine hydrochloride; 2-(Bromomethyl)-3-fluoropyridine hydrochloride; 3-Fluoro-2-pyridinemethanol, bromo-, hydrochloride; (3-Fluoro-2-pyridinyl)methyl bromide hydrochloride; 2-Bromomethyl-3-fluoropyridine HCl
EINECS	Contact for details

Quality Control

Every batch of 2-(Bromomethyl)-3-Fluoropyridine Hcl is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.