Description

Imidodicarbonic Acid, 2-(4-Chloro-3H-Imidazo[4,5-C]Pyridin-4-Yl)-, 1,3-Bis(1,1-Dimethylethyl) Ester is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for medicinal chemistry research and development, offering a protected, reactive scaffold for constructing novel heterocyclic molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers specializing in oncology, antiviral, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly in oncology and antiviral research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring the imidazo[4,5-c]pyridine core structure.
• Chemical Biology Probes: Employed in the development of chemical probes and tool compounds for target validation and biological pathway studies.
• Process Development: Supports scale-up and process chemistry development for new drug substances in pre-clinical and clinical stages.
• Contract Research & Manufacturing (CRO/CMO): Essential material for organizations providing custom synthesis and development services to the biopharma industry.

Basic Information

Product Name	Imidodicarbonic Acid, 2-(4-Chloro-3H-Imidazo[4,5-C]Pyridin-4-Yl)-, 1,3-Bis(1,1-Dimethylethyl) Ester
CAS No.	1523571-14-3
Molecular Formula	C17H21ClN4O4
Molecular Weight	380.83 g/mol
Synonyms	Di-tert-butyl 2-(4-chloro-3H-imidazo[4,5-c]pyridin-4-yl)imidodicarbonate; 2-(4-Chloro-3H-imidazo[4,5-c]pyridin-4-yl)-1,3-bis(tert-butoxycarbonyl)imidazolidine-4,5-dione; 4-Chloro-4H-imidazo[4,5-c]pyridine-2,6-dicarboxylic Acid Bis(1,1-dimethylethyl) Ester; tert-Butyl 2-(4-chloro-3H-imidazo[4,5-c]pyridin-4-yl)imidodicarbonate; BOC-Protected 4-Chloroimidazopyridine Derivative; 1523571-14-3; 4-Chloroimidazo[4,5-c]pyridine Di-BOC Ester
EINECS	Contact for details

Quality Control

Our Imidodicarbonic Acid, 2-(4-Chloro-3H-Imidazo[4,5-C]Pyridin-4-Yl)-, 1,3-Bis(1,1-Dimethylethyl) Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.