Description

6-Oxa-2-Azaspiro[3.4]Octane Oxalate (2:1) is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure, which is critical for imparting specific conformational and biological properties to target molecules. This compound matters because it serves as a sophisticated building block in modern drug discovery, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced efficacy and selectivity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with the spiro[3.4]octane core.
• Process Chemistry Development: Serves as a starting material or advanced intermediate for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development of complex molecules for clinical trials.
• Academic Research: Utilized in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	6-Oxa-2-Azaspiro[3.4]Octane Oxalate (2:1)
CAS No.	1523571-05-2
Molecular Formula	C7H11NO2 • 0.5 C2H2O4
Molecular Weight	Contact for details
Synonyms	6-Oxa-2-azaspiro[3.4]octane oxalate (2:1); 2:1 Salt of 6-Oxa-2-azaspiro[3.4]octane and oxalic acid; 6-Oxa-2-azaspiro[3.4]octane hemioxalate; Oxaspirooctane oxalate salt; Azaspirooctane oxalate; Spirocyclic oxazolidine oxalate; CAS 1523571-05-2
EINECS	Contact for details

Quality Control

Our 6-Oxa-2-Azaspiro[3.4]Octane Oxalate (2:1) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC, to ensure it meets the stringent requirements for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.